Development of an Enzyme-Linked Immunosorbent Assay for Detection of the Native Conformation of Enterovirus A71

ABSTRACT Enterovirus A71 (EVA71) is a medically important virus that is commonly associated with hand, foot, and mouth disease (HFMD).It is responsible for periodic outbreaks, resulting in significant economic impact and loss of life.Vaccination offers the potential to control future outbreaks, and vaccine development has been increasingly the focu

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Laparoscopic Pelvic Floor Repair Using Polypropylene Mesh

Objective: The purpose of this report is to present our experience in laparoscopic pelvic floor repair using polypropylene mesh for the treatment of advanced vaginal vault prolapse and enterocele.Materials and Methods: A total of 40 patients with Baden-Walker System grade 3 or 4 vaginal vault prolapse and concurrent enterocele were recruited.Twenty

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International consensus validation of the POPI tool (Pediatrics: Omission of Prescriptions and Inappropriate prescriptions) to identify inappropriate prescribing in pediatrics.

IntroductionWhile drug prescription should be based on established recommendations stemming from clinical trials but in pediatrics, many drugs are used without marketing authorization.Consequently recommendations are often based on clinical experience and the risk of inappropriate prescription (IP) is high.A tool for detecting IP in pediatrics-call

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Unravelling Antigenic Cross-Reactions toward the World of Coronaviruses: Extent of the Stability of Shared Epitopes and SARS-CoV-2 Anti-Spike Cross-Neutralizing Antibodies

The human immune repertoire retains the molecular memory of a very great diversity of target antigens (epitopes) and can recall Nail Biting this upon a second encounter with epitopes against which it has previously been primed.Although genetically diverse, proteins of coronaviruses exhibit sufficient conservation to lead to antigenic cross-reaction

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